The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene.
نویسندگان
چکیده
Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described.
منابع مشابه
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عنوان ژورنال:
- Memorias do Instituto Oswaldo Cruz
دوره 98 3 شماره
صفحات -
تاریخ انتشار 2003